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Multiple barriers to the safety and availability of blood components for transfusion were identified in the 2015 Global Database on Blood Safety, many of which derive from weak regulatory oversight, insufficient financing, and fragmentation of the national blood system. Centralization of key functions of the blood service within a limited number of blood establishments, particularly testing and processing of blood donations, can overcome several shortcomings that often exist in decentralized blood systems that are highly fragmented.
The "How do I" is a series of practical tips from Working Party members (experts) about specific contents that are hard to find in textbooks but might exist already.